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KMID : 0358420090520020212
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Korean Journal of Obstetrics and Gynecology
2009 Volume.52 No. 2 p.212 ~ p.219
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Clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma
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Woo Hee-Joung
Kim Sang-Heon
Kim Ki-Dong
Park Sang-Il
Song Yong-Jung
Kim Beob-Jong
Kim Moon-Hong
Choi Suck-Chul
Ryu Sang-Young
Lee Eui-Don
Lee Kyung-Hee
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Abstract
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Objective: The objective of this study was to examine the clinicopathologic characteristics and prognostic factors of primary peritoneal carcinoma (PPC).
Methods: Clinicopathologic variables were obtained by examining the medical records of patients with PPC who were diagnosed and treated at our institute, between January 1996 and December 2005. To find prognostic factors, the association of clinicopathologic variables with survival was evaluated by univariate and multivariate analysis.
Results: All patients had advanced-stage tumors. Residual tumor was smaller than 1 cm in 12 patients and was equal or larger than 1 cm in nine patients. The response rate to adjuvant chemotherapy was 47.6%. The median progression-free survival was eight months (range 1~95) and the median overall survival was 14 months (range 1~99). In univariate analysis, stage, the response to adjuvant chemotherapy, and neoadjuvant chemotherapy were associated with survival. However, in multivariate analysis, no variables were associated with survival.
Conclusion: In spite of aggressive treatments, patients with PPC had poor prognosis. No prognostic factors were identified in this study.
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KEYWORD
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Primary peritoneal carcinoma, Overall survival, Prognostic factor
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